Aurum Metallicum: This remedy is prescribed by homeopaths to alleviate feelings of worthlessness, low self-esteem, and despair. It can help provide hope for a person with reactive depression, and is said to be particularly beneficial to those generally hard-working individuals who have had life-altering events that they feel suggest failure on their part. This type of person is usually idealistic and goal-oriented.

Ignatia: In instances of depression caused by an event that produces profound sadness or grief, such as the loss of a loved one, and in which those feelings of deep sorrow are obvious, ignatia is prescribed.

Natrum Muriaticum: This treatment, like ignatia, is also used when depression is caused by an event that generates profound bereavement and distress. However, the difference is that this one is used for those individuals who cannot show their feelings. This is for people who appear strong and controlled and suffer in silence.

Sepia: This remedy is used mainly for women going through menopause. While depression associated with menopause often appears and disappears at random, or for no apparent reason, the depression the woman feels is quite real and intense. She may feel disconnected from everything that once gave her pleasure, including family and friends. This type of depression can be characterized by irritability and indifference to others.

Pulsatilla: This is generally used for people who show signs of manic depression.